Depletion of vitamins chart - herbs, supplements Depletion of Vitamins
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Drug/Substance  Nutrients Depleted
Alcohol  Magnesium, B Complex, C, D, E, K
Allopurinol Iron
Anorectic Agents 
(Including Amphetamines)
Vitamin B-12, C, Potassium
Antacids Vitamin B-1, B-2, D, Folic Acid, Iron, Phosphates
Antibiotics Vitamin A, B-12, C, E, K, Biotin, Calcium, Iron, Magnesium, Potassium
Anticonvulsants Vitamin B-2, B-12, C, F, K, Folic Acid, Calcium, Magnesium
Antidiabetics (Oral) Vitamin B-2, B-12, C, D, Folic Acid
Antihistamines Vitamin C
Antituberculosis Drugs Vitamin B-6, B-12, C, E, K, Folic Acid, Iron (by GI blood Loss)
Aspirin Calcium, Folic Acid, Iron, Potassium, C, B Complex
Barbituates Vitamin C
Caffeine Biotin, Inositol, Potassium, A, B Complex, C
Cardiac Glycosides Vitamin D, Calcium, Magnesium
Chelators Copper, Iron, Magnesium, Zinc
Cholestyramine Vitamin A, B-12, D, E, Folic Acid, Iron
Colfibrate Vitamin A, B-12, Iron, K
Colchicine Vitamin B-12
Contraceptive Steroids (oral) Vitamin B-1, B-2, B-6, B-12, C, E, Folic Acid, Niacin
Corticosteroids Vitamin B-2, C, D, Niacin, Zinc
Cycloserine Vitamin B-12, Folic Acid, K, Calcium, Magnesium
Digitalis Vitamin B-1
Diuretics B-1, B-12, Folic Acid, Potassium, Zinc, Calcium, Magnesium
Estrogen Folic Acid, B-6
Ghicocorticoids B-2, C, D, Niacin, Calcium, Potassium, Zinc
Glutethimide Vitamin D
Hydralizine Vitamin B-6
Irritant Cathartics Vitamin D
Isoniazid Vitamin B-6, Niacin
Laxatives (excluding herbs) Vitamin A, B-2, B-12, D, Folic Acid, Iron, Phosphate, Calcium, Potassium
Methotrexate Folic Acid
Mineral Oil Vitamin A, D, E, K
Muscle Relaxers Vitamin B-2, B-12, C, D, Folic Acid
Neomycin Vitamin A, B-2, B-6, B-12, Iron
Penicillamine Vitamin B-6, Copper, Zinc
Potassium Chloride Vitamin B-12 
Pyrimethamine Folic Acid
Sulfasalazine Folic Acid
Tetracycline Vitamin C
Triamterene Folic Acid
Trimethoprim Folic Acid